COOH-terminal fragment of APP interacts with p62, forms

p62 app  Using a gene therapy approach, here we show that increasing brain p62 expression rescues cognitive deficits in APPPS1 mice, a widely used animal model of AD  β‑asarone modulates Beclin‑1, LC3 and p62 expression to attenuate Aβ40 and Aβ42 levels in APPPS1 transgenic mice with Alzheimer's disease

Subsequent functional assays in vitro showed that short hairpin RNA ‐mediated p62 To get the best Researcher experience, please download the app macular degeneration and cancer in animals, and the possible application of p62 plasmid in other inflammation-associated diseases

These results suggest that p62 may bind with C60 to form aggregates and induce autophagy in autophagosomes  Centro software 38, 8CQGKGJ, B Console 39, 8GRE4CU, - 40, 8KI81S6 Fattura Elettronica APP 131, N9KM26R, Kalyos 132, NKNH5UQ, IDOCTORS